GLP-1 receptor agonists like Mounjaro® (tirzepatide), Ozempic® (semaglutide), Wegovy®, Zepbound®, and similar injections have transformed weight management and type 2 diabetes treatment. But as with any medication, there are both benefits and drawbacks to consider.
So what are the real pros and cons of these treatments — and where do supplements like multivitamins fit in?
Direct Answer: The pros of GLP-1 medications include weight loss, reduced appetite, and better blood sugar control. The cons include gastrointestinal side effects, cost, and the risk of nutritional gaps due to reduced food intake and absorption.
✅ Pros of Mounjaro, Ozempic & Other GLP-1 Medications
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Effective weight loss → Many patients lose 10–20% of their body weight.
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Blood sugar control → Improves insulin sensitivity and lowers HbA1c, supporting type 2 diabetes management.
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Reduced appetite → By slowing gastric emptying and reducing hunger hormones, people naturally eat less.
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Cardiovascular benefits → Some studies show reduced risk of heart events in high-risk groups.
⚠️ Cons of Mounjaro, Ozempic & Other GLP-1 Medications
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Gastrointestinal side effects → Nausea, diarrhoea, constipation, and bloating are common.
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Cost & availability → In the UK, rising costs of Mounjaro and supply issues with Ozempic/Wegovy have led to access concerns.
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Long-term dependency → Benefits often reverse if treatment stops.
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Nutritional deficiencies → Appetite suppression, smaller meals, and digestive changes can reduce intake and absorption of key vitamins and minerals.
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🧬 Nutrient Gaps on GLP-1 Medications
Because GLP-1s slow digestion and reduce appetite, you may not get enough essential micronutrients:
| Nutrient | Why It Matters | GLP-1 Risk Factor |
|---|---|---|
| Iron | Oxygen transport, energy | Reduced intake + poor absorption |
| B-complex (B12, folate, B6) | Energy, cognition, red blood cells | Lower calorie intake |
| Vitamin D₃ & K₂ | Bone health, calcium balance | Fat-soluble, less absorbed on low-fat diets |
| Magnesium | Sleep, blood pressure, muscle recovery | Lost through diarrhoea; less dietary intake |
| Zinc & Selenium | Hair, skin, thyroid health | Reduced absorption |
| Antioxidants (vitamin C, E, beta-carotene) | Protection, repair | Lower intake of fruit/veg |
These deficiencies can explain side effects people often report: fatigue, poor sleep, hair thinning, and slower recovery.
🌟 Why TRINITY by Arbor Vitamins Supports GLP-1 Users
TRINITY was designed to solve the absorption and timing problems that generic one-a-day multivitamins can’t:
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The Morning Formula combines iron bisglycinate with vitamin C for enhanced absorption, alongside a full methylated B-complex for energy and clarity.
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The Day Formula delivers vitamin D₃ + K₂ to balance calcium and protect bones, with B6, B12 (methylcobalamin), chromium, and iodine for hormone and blood sugar regulation.
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The Night Formula provides magnesium glycinate, zinc, selenium, molybdenum, and vitamin E to support rest, repair, and thyroid function.
✅ Nutrient synergy → pairs that work together (iron + C, D₃ + K₂)
✅ No clashes → separates iron from calcium, zinc from copper, etc.
✅ Bioavailable forms → methylfolate, methylcobalamin, bisglycinates
✅ Clean & vegan → no fillers, binders, maltodextrin, or seed oils
🧠 Summary
GLP-1 medications like Mounjaro, Ozempic, Wegovy, Zepbound, and other semaglutide/tirzepatide injections offer major health benefits for weight loss and diabetes management. But they also carry downsides: digestive issues, high cost, and the risk of nutrient deficiencies.
A high-quality, well-absorbed multivitamin like TRINITY can help cover these nutritional gaps — supporting energy, immunity, bone strength, and recovery while you’re on treatment.
❓ FAQs: Pros & Cons of GLP-1 Medications
Q: What are the biggest pros of Mounjaro and Ozempic?
A: Weight loss, appetite suppression, and better blood sugar control.
Q: What are the main cons?
A: Digestive side effects, high cost, dependency, and nutritional gaps.
Q: Do GLP-1s cause nutrient deficiencies?
A: Indirectly, yes — by reducing appetite, portion size, and fat absorption.
Q: Can supplements help with side effects?
A: Yes. Multivitamins can help reduce fatigue, hair thinning, and sleep issues linked to deficiencies.
