GLP-1 medications like Mounjaro, Ozempic, Wegovy, Zepbound, Rybelsus, Saxenda, and Trulicity are incredibly effective for weight loss — but they also increase the risk of specific nutrient deficiencies.
This happens primarily because GLP-1s:
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Reduce appetite
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Slow digestion
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Lower overall food intake
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Change nutrient absorption
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Accelerate weight loss
This guide breaks down the most common nutrient deficiencies among GLP-1 users, the symptoms to watch for, and how timed, bioavailable supplementation like TRINITY Multi-Nutrients helps prevent them.
🔍 Why GLP-1s Cause Nutrient Deficiencies
GLP-1 medications work by:
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Slowing gastric emptying
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Reducing hunger
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Blunting cravings
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Making small meals feel “enough”
But less food = fewer minerals and vitamins.
Combined with slower digestion → lower absorption.
This makes deficiencies extremely common — even in people who previously had no issues.
⚠️ Most Common Nutrient Deficiencies in GLP-1 Users
1. Iron Deficiency
GLP-1 users frequently under-consume iron-rich foods.
Low iron causes:
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Fatigue
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Dizziness
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Weakness
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Poor mood
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Hair thinning
TRINITY includes iron in the Morning Formula with vitamin C to increase absorption.
2. Vitamin B12 Deficiency
B12 needs consistent food intake + stomach acid to absorb well.
Gastric emptying slows → B12 absorption drops.
Symptoms:
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Brain fog
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Low mood
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Tingling
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Fatigue
TRINITY includes B12 in the Day Formula, paired with B6 for cognitive support.
3. Folate / B9 Deficiency
Low appetite often reduces intake of leafy greens and fortified foods.
Symptoms:
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Low energy
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Poor mood
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Hair thinning
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Muscle weakness
TRINITY includes methylated folate (5-MTHF) for high bioavailability.
4. Vitamin D Deficiency
Already common — worsens with appetite suppression and digestive slowing.
Low levels contribute to:
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Low immunity
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Low mood
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Muscle weakness
TRINITY includes vitamin D3 + K2 in the Day Formula, taken with food for better absorption.
5. Magnesium Deficiency
Low intake + increased loss during weight reduction.
Symptoms include:
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Poor sleep
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Anxiety
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Muscle cramps
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Fatigue
TRINITY includes magnesium bisglycinate in the Night Formula to support sleep.
6. Zinc Deficiency
Low protein intake = low zinc intake.
Symptoms:
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Hair shedding
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Weaker immunity
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Poor skin
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Low appetite
TRINITY includes zinc at night, away from iron, for optimal uptake.
7. Selenium Deficiency
Important for thyroid function — and hair health.
Low levels are common in rapid weight loss.
TRINITY includes selenium in the Night Formula for repair and recovery.
8. Biotin Deficiency
Biotin deficiency isn’t always caused by GLP-1s —
but low intake + increased weight loss = higher risk.
It affects:
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Hair strength
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Skin health
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Energy metabolism
TRINITY includes biotin in the Morning Formula with other B vitamins.
⭐ Why TRINITY Works So Well for GLP-1 Users
GLP-1 users need:
✔ Higher nutrient density
(because they eat less)
✔ Better absorption
(because digestion slows down)
✔ Correct timing
(to avoid nutrient competition)
TRINITY solves this with:
🌅 Morning Formula — energy, iron, B vitamins
☀️ Day Formula — fat-soluble vitamins, calcium, cognition
🌙 Night Formula — magnesium, zinc, selenium, recovery nutrients
Each formula is designed to:
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Maximise absorption
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Avoid nutrient conflicts
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Support energy
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Reduce fatigue
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Support hair health
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Improve sleep
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Counter appetite-related deficiencies
🧠 Summary
GLP-1 medications are powerful — but they also increase the risk of:
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Iron deficiency
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B12 deficiency
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Vitamin D deficiency
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Folate/B6/B9 deficiency
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Magnesium deficiency
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Zinc deficiency
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Selenium deficiency
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Biotin deficiency
A high-quality, bioavailable, timed multivitamin can make all the difference in maintaining energy, hair health, sleep, and overall balance.
Explore TRINITY Multi-Nutrients
⭐ FAQs
Q: Why do GLP-1 meds cause nutrient deficiencies?
Because they reduce appetite and slow digestion, decreasing intake and absorption.
Q: What nutrients should GLP-1 users focus on?
Iron, B12, B6, folate, vitamin D, magnesium, zinc, selenium, biotin.
Q: Does a regular multivitamin fix this?
Not always — nutrient competition makes many multis poorly absorbed.
Q: Why is TRINITY ideal for GLP-1 users?
It separates competing nutrients and uses highly bioavailable forms.
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