GLP-1 medications like Mounjaro, Ozempic, Wegovy, Zepbound, Rybelsus, Trulicity, and Saxenda are transforming weight loss and metabolic health.
But they also come with unique side effects — many of which are linked to reduced appetite, lower nutrient intake, slower digestion, and changes in metabolism.
If you're on a GLP-1, understanding these side effects and supporting your body with the right nutrients is crucial.
This guide breaks down:
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The most common GLP-1 side effects
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How GLP-1s affect nutrient absorption
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Why fatigue, hair loss & low energy happen
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The nutrients people often miss on GLP-1s
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And why a clean, bioavailable multivitamin like
TRINITY Multi-Nutrients
is one of the most important companions to these medications
🔍 What Are GLP-1 Medications?
GLP-1 agonists include well-known brands such as:
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Mounjaro
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Ozempic
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Wegovy
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Zepbound
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Saxenda
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Rybelsus
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Trulicity
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Victoza
All of them work by:
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Slowing digestion (gastric emptying)
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Regulating blood sugar
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Reducing appetite
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Supporting weight loss
And while they are extremely effective, one thing is clear:
➤ Eating less = absorbing fewer nutrients
➤ Digesting slower = reduced nutrient uptake
➤ Rapid weight loss = increased nutrient demand
This creates the perfect storm for deficiencies — even in people who were previously healthy.
⚠️ Common GLP-1 Side Effects — And Why They Happen
1. Fatigue
One of the most reported side effects across Mounjaro, Ozempic, Wegovy, Zepbound.
Fatigue is often linked to:
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Low iron intake
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Low B12
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Low B6
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Low folate
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Low electrolytes
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Slower digestion → slower nutrient absorption
GLP-1s reduce appetite so much that people unintentionally undereat nutrition required for normal energy production.
2. Hair Thinning / Increased Shedding
Not everyone experiences this — but people who do often ask:
“Is it the medication, or am I under-nourished?”
The answer:
Hair loss is most commonly linked to:
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Low biotin
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Low iron (very common on GLP-1s)
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Low zinc
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Low selenium
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Low protein intake
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Very rapid weight loss
These are some of the exact nutrients TRINITY supports.
3. Muscle Loss & Weakness
GLP-1s help you lose weight — but they don’t distinguish between:
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Fat
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Muscle
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Water
Low appetite = low protein intake → muscle loss accelerates.
Nutrients like magnesium, B vitamins, selenium, and iron help maintain energy production and healthy muscle function.
4. Digestive Issues (Nausea, Constipation)
Because gastric emptying slows down, digestion becomes less efficient — affecting nutrient absorption.
This is another reason a high-quality, bioavailable multivitamin is important.
🧪 Why Nutrient Deficiencies Rise on GLP-1 Medications
GLP-1s lower appetite so dramatically that many people:
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Skip meals
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Eat fewer nutrient-dense foods
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Consume smaller portion sizes
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Reduce protein intake
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Forget to supplement minerals
This leads to deficiencies in:
Most at-risk nutrients:
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Iron
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B12
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B6
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Folate
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Vitamin D
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Magnesium
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Zinc
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Selenium
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Biotin
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Electrolytes
These deficiencies directly contribute to:
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Fatigue
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Hair thinning
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Poor sleep
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Mood changes
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Muscle weakness
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Skin issues
This is where timed nutrient support becomes crucial.
⭐ Why a Multivitamin Like TRINITY Is So Important for GLP-1 Users
Most multivitamins throw everything into one capsule at the same time.
This leads to nutrient competition, especially with:
❌ iron + calcium
❌ magnesium + iron
❌ zinc + copper
❌ fat-soluble vitamins without food
But because GLP-1 users already absorb nutrients less efficiently, this competition becomes an even bigger issue.
TRINITY solves this problem with:
✔ Morning Formula (energy nutrients)
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Iron + vitamin C
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Full B-complex
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Folate
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Biotin
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Magnesium malate
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Turmeric + piperine
Boosts energy, cognition, and iron absorption — perfect for GLP-1 users feeling fatigued.
✔ Day Formula (fat-soluble vitamins + bone + immune)
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Vitamin D3 + K2
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Calcium
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Iodine
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B6 & B12
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Lutein + zeaxanthin
Helps with nutrient gaps caused by appetite suppression.
✔ Night Formula (recovery + repair)
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Magnesium glycinate
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Zinc
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Selenium
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Vitamin E
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B3 (nicotinamide)
Supports sleep, repair, hair health, and recovery.
Explore TRINITY Multi-Nutrients

🧠 Summary
GLP-1 medications like Mounjaro, Ozempic, Wegovy, and Zepbound are incredibly effective — but they naturally increase the risk of:
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Fatigue
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Hair thinning
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Nutrient deficiencies
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Low energy
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Digestive changes
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Muscle loss
A multivitamin that supports bioavailability, nutrient synergy, and AM/PM timing is one of the smartest tools you can use on these medications.
⭐ FAQs
Q: Do GLP-1 medications cause nutrient deficiencies?
Yes — reduced appetite and slower digestion affect nutrient intake and absorption.
Q: Why do GLP-1 users feel tired?
Low iron, B12, B6, folate, magnesium, and electrolytes contribute to fatigue.
Q: Does Mounjaro cause hair loss?
Indirectly — rapid weight loss + low nutrient intake can trigger shedding.
Q: What supplements should I take on GLP-1s?
Iron, B vitamins, magnesium, zinc, selenium, and fat-soluble vitamins are key.
Q: Why is TRINITY good for GLP-1 users?
It separates competing nutrients and supports absorption morning → night.
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